Effect of 10Hz rTMS as an adjunctive to pregabalin in addition to Pregabalin in Central Post Stroke Pain : A randomised double blind placebo controlled trial
- Conditions
- Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere
- Registration Number
- CTRI/2024/07/071057
- Lead Sponsor
- Professor Jayantee Kalita
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Age more than 18 years, those fulfilling the diagnostic criteria of CPSP, pain intensity more than equal to 4 on a Visual analog scale (VAS, 0 to 10 with 0 indicating no pain and 10 the worst pain imaginable), those who will give the consent to participate in the study
Age more than 70 years and less than 18 years, patients with less than 4 pain on VAS, epilepsy, pregnancy, metallic implant, pacemaker, painful peripheral neuropathy, complex regional pain syndrome, psychiatric and post-head injury pain disorders, bony defect of scalp, chronic renal or liver failure, heart failure, cancer, and those with a history of drug allergy will be excluded. The patients with dementia and aphasia, and those who are not willing to give consent will also be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Greater than 50% reduction in pain on visual analog scale.Timepoint: Baseline, 1 month and at 3 months
- Secondary Outcome Measures
Name Time Method 1. Reduction in pain from baseline on visual analog scale (VAS) <br/ ><br>2. Improvement in scores of Neuropsychiatric Inventory (NPI), Hospital anxiety depression <br/ ><br>scale (HADS) score, Pittsburgh sleep quality index (PSQI), Quality of life index (QOL), <br/ ><br>Median Somatosensory evoked potentials, Mechanical static, Mechanical dynamic <br/ ><br>allodynia and Cold allodynia.Timepoint: baseline, 1 month and at 3 months