Comparison of the effectiveness of ketamine with buprenorphine in depression associated with opium use

Not Applicable

Recruiting

• Conditions: Condition 1: Depression. Condition 2: Suicide idea. Condition 3: Opioids abuse.; Major depressive disorder, single episode; Other symptoms and signs involving emotional state; Mental and behavioural disorders due to use of opioids; R45.8

• Registration Number: IRCT20211214053411N1
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients admitted to Ebn Sina Hospital in Shiraz with a diagnosis of major depression or depression induced by opioid use
Age between 18 and 60 years
Opium user according to DSM5 criteria

Exclusion Criteria

Having a major comorbid psychiatric illness such as psychosis or bipolar spectrum
Having major physical illnesses such as cardiovascular disease - Uncontrolled blood pressure - Uncontrolled diabetes - Uncontrolled thyroid disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression. Timepoint: Before the intervention, the day of the intervention, 24 hours after the intervention, one week after the intervention. Method of measurement: Beck Depression Inventory.

Secondary Outcome Measures

Name	Time	Method
Anxiety. Timepoint: Before the intervention, the day of the intervention, 24 hours after the intervention, one week after the intervention. Method of measurement: Hamilton Anxiety Questionnaire.;Suicide idea. Timepoint: Before the intervention, the day of the intervention, 24 hours after the intervention, one week after the intervention. Method of measurement: Beck suicide questionnaire.