Effect of Acetaminophen on relief of bone pain due to PEG G-CSF
Phase 3
- Conditions
- Bone Pain Due to PEG G-CSF.Non-follicular lymphoma
- Registration Number
- IRCT20190514043586N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
People with Solid Tumor or Lymphoma who receive PEG G-CSF due to neutropenia after chemotherapy
Exclusion Criteria
Bone matastasis
PFS more than 2
Osteomalacia proven with laboratory tests
CKD or ESRD
Active Rheumatologic disease
Uncontrolled Diabetes or Thyroid disease
Patients receiving chemotherapy drugs that have bone pain are a high prevalence of 10% (TAXAN family, bisphosphonate ...)
Pathologic fracture or fracture due to any reason
Naproxen use contraindication
Vitamin D level less than 20
Paget disease
Hyperparathyroidism
People who have had a score of over 6 in the bone pain score since the beginning of the project
Liver disease
History of Cardiac Arrhythmia
Patient who have not compliance for completing pain questionnaire
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Score in Visual Analogue Scale(VAS) questionnaire. Timepoint: Day 0; One day after the end of first and third course of chemotherapy. Method of measurement: Visual Analogue Scale questionnaire.
- Secondary Outcome Measures
Name Time Method