Comparison of the effectiveness and complication of dexamethasone at doses of 8 and 24 mg in the treatment of in Hospitalized Patients with Covid-19
Phase 3
Recruiting
- Conditions
- covid 19 pneumonia.Multisystem inflammatory syndrome associated with COVID-19
- Registration Number
- IRCT20190606043826N2
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Hospitalized Patients with Covid-19
Exclusion Criteria
Pregnancy
Immunodeficiency diseases
chronic liver and kidney diseases or gastrointestinal bleeding
Glucocorticoid use in the last 1 month
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determination of mean arterial blood oxygen saturation with and without oxygen therapy. Timepoint: At the beginning of hospitalization and 3, 5, 7 and 10 days later. Method of measurement: pulse oxymeter.;Shortness of breath score based on modified Borg scale. Timepoint: At the beginning of hospitalization and 3, 5, 7 and 10 days later. Method of measurement: modified Borg scale.;Number of days required for mechanical ventilation. Timepoint: daily. Method of measurement: Counting days under mechanical ventilation.;Measurement of serum levels of C-reactive protein. Timepoint: At the beginning of hospitalization and 3, 5, 7 and 10 days later. Method of measurement: laboratory test.
- Secondary Outcome Measures
Name Time Method