A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis

Not Applicable

• Conditions: Malignant Pleural Effusions; Recurrent Pleural Effusions; Primary Spontaneous Pneumothorax; Secondary Spontaneous Pneumothorax

• Registration Number: NCT00430664
• Lead Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

Brief Summary

Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is done to get rid of collections of fluid or air in this space. A common reason would be cancer of the underlying lung or elsewhere causing fluid to collect in the pleural space. In this situation it is a palliative procedure to free the patient from symptoms like breathlessness.

Detailed Description

Pleurodesis is a technique used to fuse the two layers of the pleura. This is done to prevent reaccumulation of collections of fluid or air in this space. Common indications are malignant pleural effusions, recurrent pneumothorax and even benign effusions which are otherwise difficult to eradicate.

Study Timeline

• Study Start: 2006-01
• Status Verified: 2007-02
• Study First Submitted: 2007-02-01
• Study First Submitted QC: 2007-02-01
• Last Update Submitted: 2007-02-01
• Study First Posted: 2007-02-02
• Last Update Posted: 2007-02-02
• Study Completion: 2007-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age over 12 years
• Symptomatic recurrent pleural effusion
• Pneumothorax needing pleurodesis

Exclusion Criteria

• Life expectancy <1 month
• Unwilling to give consent
• Empyema
• ICTD drain output >150 ml/d
• Presence of an airleak

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Success
Failure

Secondary Outcome Measures

Name	Time	Method
Death
Pain by VAS
Time to Pleurodesis
Others

Trial Locations

Locations (1)

PGIMER; 🇮🇳 Chandigarh, India