Oral (Hypo-)function, General Function and Nutritional Status in Elderly Hospitalized Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 2
- 主要终点
- Malnutrition status as classified by the Global Leadership Initiative on Malnutrition (GLIM)
研究概览
简要总结
The goal of this observational study is to learn about the effects of a reduced oral function on the nutritional status of non-acute hospitalized elders and on their oral health quality of life.
详细描述
Malnutrition is highly prevalent among the elderly, many authors reported on the relationship between oral health and nutrition. However the the relationship between the dental state and the nutritional status was always limited to anatomical criteria such as number of teeth and the presence of prosthetic reconstructions.
The oral function is classified into 4 stages healthy state, oral frailty, oral hypofunction and oral dysfunction. The classification into the different stages result from an examination of 7 parameters: the oral hygiene, the oral dryness, the occlusal force, the tongue-lip motor function, the tongue pressure, the chewing function and the swallowing function.
This study aims to correlate the oral function with the nutritional status of non-acute hospitalized elders. And to further investigate the correlation between the different parameters defining the oral function and the oral health related quality of life (OHRQoL) as measured by theGeneral Oral Health Assessment Index.
A total 60 participants will be recruited in the University Hospital of Geneva, Loëx rehabilitation center. The investigators will see the patient for 2 visits after informed consent. The first visit will be 45 minutes long and will include a dental examination and an examination of the oral hygiene, the oral dryness, the tongue lip motor function, the tongue pressure, the occlusal force and the swallowing function. Diagnosis for nutrition according to the Glim criteria will be done. Furthermore, the participants will be asked to fill an oral health quality of life questionnaire comprising 12 questions.
Oral hypo function will be defined as a state when 3 or more signs were present from the 7 parameters examined.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •• Aged 70 years or over
- •Hospitalized in Geneva University Hospitals, in rehabilitation or in long term care (Loëx)
- •Able to follow simple instructions and perform the tests
- •Understand French and complete or answer the questionnaire
- •Give written informed consent
- •Consent can be obtained from their next of kin or legal representative if necessary
- •Have been admitted into the hospital no longer 15 days before inclusion
排除标准
- •Patients with tube/intravenous feeding
- •Poorly-controlled diabetes (Liu et al., 2015)
- •Patients with gastro-intestinal diseases or symptoms (nausea, vomiting, diarrhea, constipation) affecting oral intake
- •If the patient is taking an antimicrobial treatment at this time.
结局指标
主要结局
Malnutrition status as classified by the Global Leadership Initiative on Malnutrition (GLIM)
时间窗: baseline
The GLIM considers both (a) phenotypic (\>5% weight loss within the previous 6 months or \>10% weight loss in more than 6 months, BMI \< 22 kg/m2 if age \>70 years, FFMI \<17 kg/m2 in men and \<15 kg/m2 in women) and (b) aetiologic criteria (reduced food intake and level of inflammation with CRP \>10 mg/L). Participants were classified as malnourished when at least 1 phenotypic criterion and 1 aetiologic criterion were met. The severity of the malnutrition is based on the phenotypic criteria in a stage 1 "moderate malnutrition" and stage 2 "severe malnutrition." The participants were classified on a score scale from 0- 2 with o being normal, 1 for the moderate malnutrition and 2 for the severe malnutrition.
Number of impaired oral functions
时间窗: baseline
The Japanese society of gerodontology in 2016 published a position paper aiming to standardize the examination of oral disorders related to age and to suggest management strategies. They created a conceptual diagram divided into 4 stages: healthy state, oral frailty, oral hypofunction and oral dysfunction. The classification into the different stages result from an examination of 7 parameters: the oral hygiene, the oral dryness, the occlusal force, the tongue-lip motor function, the tongue pressure, the chewing function and the swallowing function. Oral hypofunction is defined as a state when 3 or more signs were present.
次要结局
- Oral health related quality of life(baseline)
研究者
Frauke Müller
Professor
University of Geneva, Switzerland