NCT05671003已完成不适用
The Effect of Dentition, Eating Rate, Oral Processing, and Gastric Emptying on Appetite and Satiety in Older Adults (≥65 Years of Age)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 88
- 试验地点
- 1
- 主要终点
- Objective appetite assessment: Ad-libitum meal consumption
研究概览
简要总结
The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old. The main question it aims to answer is if oral processing affects gastric emptying in older adults (≥65 years old).
详细描述
- To investigate if food intake and satiety differ between faster and slower eaters, within older adults (≥65 years old).
- To assess if chewing rate, salivary flow rate, oral processing and gastric emptying differ between older adults (≥65 years old) with smaller versus bigger appetites.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •65 years old or over (no upper age limit);each group will contain an equal number of male and female participants;
- •living sufficiently local to attend the two visits needed;
- •able to understand and communicate in English language.
排除标准
- •Diagnosed dysphagia;
- •(recent) oral surgery that significantly affects eating and/or swallowing;
- •diagnosis of type 1 or type 2 diabetes;
- •participant undergoing current treatment for cancer;
- •participants with zero natural teeth;
- •severe loss of appetite and not able to finish a meal (based on CNAQ) and/or people on special or therapeutic diets that restrict the consumption of a full meal and/or the meals provided;
- •not able to provide informed consent as defined by the T-CogS test (participants with T-CogS < 22 will be excluded);
- •participants having a pacemaker;
- •not able to accept the two meal dishes provided and/or relevant food/ingredient included in the meals allergies or intolerances or aversions;
- •not able to feed themselves.
结局指标
主要结局
Objective appetite assessment: Ad-libitum meal consumption
时间窗: During the procedure
Consumption of the ad-libitum meal is measured (g). Participants are instructed to eat until they feel comfortable full
次要结局
- BMI(During the procedure)
- Oral Health(During the procedure)
- Subjective appetite assessment: VAS(During the procedure)
- Salivary a-amylase(During the procedure)
- Salivary flow rate(During the procedure)
- Glucose(During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours)
- Gastric Emptying(During the procedure)
- Chewing rate(During the procedure)
- Chewing ability(During the procedure)
- Insulin(During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours)
研究者
Miriam Clegg
Associate Professor
University of Reading
研究点 (1)
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