The Effect of Dentition, Eating Rate, Oral Processing, and Gastric Emptying on Appetite and Satiety in Older Adults (≥65 Years of Age)

University of Reading1 site in 1 country88 target enrollmentJanuary 15, 2023

ConditionsOlder Adults Appetitive Behaviour Food Intake Oral Processing

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Older Adults
Sponsor: University of Reading
Enrollment: 88
Locations: 1
Primary Endpoint: Objective appetite assessment: Ad-libitum meal consumption
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old. The main question it aims to answer is if oral processing affects gastric emptying in older adults (≥65 years old).

Detailed Description

* To investigate if food intake and satiety differ between faster and slower eaters, within older adults (≥65 years old). * To assess if chewing rate, salivary flow rate, oral processing and gastric emptying differ between older adults (≥65 years old) with smaller versus bigger appetites.

Registry

clinicaltrials.gov

Start Date

January 15, 2023

End Date

September 15, 2023

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Reading

Responsible Party

Principal Investigator

Miriam Clegg

Associate Professor

University of Reading

Eligibility Criteria

Inclusion Criteria

•65 years old or over (no upper age limit);each group will contain an equal number of male and female participants;
•living sufficiently local to attend the two visits needed;
•able to understand and communicate in English language.

Exclusion Criteria

•Diagnosed dysphagia;
•(recent) oral surgery that significantly affects eating and/or swallowing;
•diagnosis of type 1 or type 2 diabetes;
•participant undergoing current treatment for cancer;
•participants with zero natural teeth;
•severe loss of appetite and not able to finish a meal (based on CNAQ) and/or people on special or therapeutic diets that restrict the consumption of a full meal and/or the meals provided;
•not able to provide informed consent as defined by the T-CogS test (participants with T-CogS \< 22 will be excluded);
•participants having a pacemaker;
•not able to accept the two meal dishes provided and/or relevant food/ingredient included in the meals allergies or intolerances or aversions;
•not able to feed themselves.

Outcomes

Primary Outcomes

Objective appetite assessment: Ad-libitum meal consumption

Time Frame: During the procedure

Consumption of the ad-libitum meal is measured (g). Participants are instructed to eat until they feel comfortable full

Secondary Outcomes

BMI(During the procedure)
Oral Health(During the procedure)
Subjective appetite assessment: VAS(During the procedure)
Salivary a-amylase(During the procedure)
Salivary flow rate(During the procedure)
Glucose(During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours)
Gastric Emptying(During the procedure)
Chewing rate(During the procedure)
Chewing ability(During the procedure)
Insulin(During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours)