Neurological Changes With a Memory Self-efficacy Training Protocol
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Neurological bio-markers: Regional activation
研究概览
简要总结
Confidence in one's ability to accomplish a task, more formally known as self-efficacy, is an important psychological variable that can influence how the investigators perform on various tasks. Previous studies have shown that self-efficacy is a modifiable trait that can be improved and bolstered with training and practice. More importantly for this study, memory self-efficacy has been shown to be modifiable for older adults, consequently improving their performance on memory tasks. While there is evidence to support the importance of memory self-efficacy for successful memory performance in older adults, the underlying neurological changes that accompany these performance changes have not been explored. The goal of this study is to examine the changes in brain activity before and after a memory self-efficacy training program to better understand the mechanisms of both memory and self-efficacy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Participants will be unaware of the content of alternate groups. Both arms will be described as "Learning and Aging" groups to the participants
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjective memory complaints within past 5 years
- •Objective memory impairment below age norms on standardized cognitive testing
- •Score below 25 on Montreal Cognitive Assessment
- •Scores 1.5 standard deviations below age norms on memory testing
- •Unimpaired performance in Activities of Daily Living
- •Intact general cognition
- •Fluently read, write and speak English
- •Right handed
排除标准
- •Co-morbidity that would impact cognition (depression, anxiety, stroke)
- •Prior diagnosis of dementia of any type
- •Use of prescription or recreational drug use that would impact cognition (excluding hormone replacement therapy)
- •Uncorrected visual or auditory deficits/impairments
- •Current participation in alternate study
研究组 & 干预措施
Memory Self-Efficacy Training
Memory self-efficacy group training classes.
干预措施: Memory Self-Efficacy Training (Behavioral)
General Education Group
General education group classes (e.g., exercise, diet, sustainability, tc.)
干预措施: General Education (Behavioral)
结局指标
主要结局
Neurological bio-markers: Regional activation
时间窗: Pre and Post intervention - 6 weeks
Using fMRI identify changes in activation patterns or signal change when performing an associative memory task
Neurological bio-markers: Default mode network
时间窗: Pre and Post intervention - 6 weeks
Using fMRI during a resting state observe changes in default mode network activation
次要结局
- Story Recall - Trained memory performance task(Pre and Post intervention - 6 weeks)
- Face-Name Pairs - Trained memory performance tasks(Pre and Post intervention - 6 weeks)
- Digit Span Task - Untrained memory performance tasks(Pre and Post intervention - 6 weeks)
- List Recall - Trained memory performance tasks(Pre and Post intervention - 6 weeks)
- RAVLT - Untrained memory performance tasks(Pre and Post intervention - 6 weeks)
- Visual Spatial Learning Task - Untrained memory performance tasks(Pre and Post intervention - 6 weeks)
- Face-Scene Pairs - Untrained memory performance tasks(Pre and Post intervention - 6 weeks)
研究者
Lindsay Nagamatsu
Assistant Professor
Western University, Canada