Brain stimulation, aging and cognition: Investigating neuroplasticity and cognitive enhancement following brain stimulation in healthy ageing and amnestic mild cognitive impairment.

Not Applicable

Completed

• Conditions: Mild Cognitive Impairment; Aging; Cognitive performance in healthy younger adults; Mental Health - Studies of normal psychology, cognitive function and behaviour; Neurological - Studies of the normal brain and nervous system; Neurological - Other neurological disorders

• Registration Number: ACTRN12614001052628
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-10-02
• Study Completion: 2016-08-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

a) Diagnosis of amnestic mild cognitive impairment (56 - 75 years) OR
b) Healthy adults aged between 18 - 35 years OR 56 - 75 years with no cognitive complaints.

Exclusion Criteria

* History of seizures or neurological disorders
* Current psychiatric diagnoses, alcohol or substance dependence
* Left-handed
* Presence of metal in head
* Women who are currently pregnant or lactating
* Individuals taking benzodiazepines or acetyl cholinesterase inhibitors

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
-back task (accuracy and reaction time)[30 minutes post-stimulation ];TMS-EEG evoked potential amplitudes[5 and 20 minutes post-stimulation]

Secondary Outcome Measures

Name	Time	Method
EEG oscillations[5 and 20 minutes post-stimulation]