Combined Cataract Surgery and Planned Descemetorhexis
Not Applicable
Completed
- Conditions
- Fuchs' Corneal DystrophyCataract
- Registration Number
- NCT02206594
- Lead Sponsor
- Medical College of Wisconsin
- Brief Summary
A pilot study designed to assess the feasibility of planned descemetorhexis for the treatment of Fuchs' corneal dystrophy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 2
Inclusion Criteria
- Patient >18 years old
- Willing and able to provide informed consent
Ocular Inclusion Criteria (all ocular inclusion criteria apply only to the study eye):
- Fuchs' corneal dystrophy diagnosed
- Cataract present
- Best corrected visual acuity ≤ 20/40
- Candidate for current endothelial transplant procedure (DSAEK, DMEK)
General
Exclusion Criteria
- <18 years old
- Medically unstable patient
- Monocular patient
- Unwilling or unable to provide informed consent
Ocular Exclusion Criteria (all ocular exclusion criteria apply only to the study eye):
- Corneal dystrophy other than Fuchs'
- Central corneal scar or central opacity not related to Fuchs'
- Severe nonproliferative diabetic retinopathy or proliferative diabetic retinopathy
- History of prior vitreoretinal surgery
- Advanced or unstable glaucoma
- Known steroid responders with glaucoma
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Corneal clarity as assessed by slit lamp photography Assessed up to 1 year following descemetorhexis
- Secondary Outcome Measures
Name Time Method Resolution of edema as assessed by slit lamp photography Assessed up to 1 year following descemetorhexis
Trial Locations
- Locations (1)
The Medical College of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States
The Medical College of Wisconsin🇺🇸Milwaukee, Wisconsin, United States