Assessment of neurocognitive functions in Parkinson patient who are ready for deep brain stimulation procedure as cases and similar assessment in controls who are waitlisted or refused Deep brain stimulatio
Not Applicable
- Conditions
- Health Condition 1: G20- Parkinsons disease
- Registration Number
- CTRI/2024/03/063848
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Diagnosis of idiopathic PD
2)Patient on 4 years of dopamine therapy
3)Motor fluctuations and drug-related Dyskinesias
4)IQ Cut Off more than or equal to 84, based on CPM
5)Willing to give written informed consent
6)Absence of dementia or severe cognitive impairment (HMSE score more than 23)
Exclusion Criteria
1)Leads removed due to infection, malfunction, etc.
2)Suffering from any other severe psychiatric disorder (based on clinical assessment) or substance use disorder (except caffeine & nicotine) assessed through clinical interview
3)Comorbid neurological illness (e.g., stroke, TBI, SOL)
4)Uncontrolled medical illness (e.g., diabetes, hypertension)
5)Currently receiving any form of Cognitive rehabilitation Therapy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change in cognitive functions using scale - (ACE-III ),(HMSE) (IADL) <br/ ><br>(CPM) <br/ ><br>(JM-MIDI) <br/ ><br>(UPDRS) <br/ ><br>(PDQ-39) <br/ ><br>Timepoint: At baseline and After 6 months follow up
- Secondary Outcome Measures
Name Time Method Change in cortical activity by using <br/ ><br>fNIRSTimepoint: At baseline and after 6 months follow up