Effects of Mulligan Mobilization With Movement as Compared to Kaltenborn Joint Mobilization in the Management of Knee Osteoarthritis

Not Applicable

• Conditions: Knee Osteoarthritis
• Interventions: Device: Heating pad; Device: Transcutaneous electrical nerve stimulation(TENS); Procedure: Kaltenborn joint mobilization; Procedure: Mulligan mobilization with movement (MWM); Procedure: Resistance Training exercise

• Registration Number: NCT06444945
• Lead Sponsor: Foundation University Islamabad

Brief Summary

This study is a randomised controlled trial and the purpose of this study is to determine the Effects of Mulligan mobilization with movement as compared to Kaltenborn joint mobilization in the management of knee osteoarthritis." To determine the effects of Mulligan MWM as compared to Kaltenborn joint mobilization in terms of pain, function, range of motion and gait in persons with knee osteoarthritis.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-05-27
• Status Verified: 2024-06
• Study First Submitted QC: 2024-06-05
• Last Update Submitted: 2024-06-05
• Study First Posted: 2024-06-06
• Last Update Posted: 2024-06-06
• Study Start: 2024-06-10
• Primary Completion: 2024-12-10
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Individuals aged 40-70 years (Osama et al, 2022)
• Having KOA history of no less than 3 months
• Knee pain less than 8/10 on numeric pain rating scale (NPRS).
• Radiological evidence of grade III or less on Kellgren classification
• Patients referred from rehab department

Exclusion Criteria

• Those with signs of serious pathology, such as malignancy, inflammatory disorder or infection.
• History of trauma or fractures in lower extremity.
• Signs of lumbar radiculopathy or myelopathy.
• History of knee surgery or replacement.
• Receiving intra-articular steroid therapy in the preceding two months.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mulligan MWM group	Heating pad	Group A receiving Mulligan MWM joint mobilization
Mulligan MWM group	Resistance Training exercise	Group A receiving Mulligan MWM joint mobilization
Kaltenborn mobilization group	Kaltenborn joint mobilization	Group B receiving Kaltenborn Joint mobilization
Mulligan MWM group	Transcutaneous electrical nerve stimulation(TENS)	Group A receiving Mulligan MWM joint mobilization
Mulligan MWM group	Mulligan mobilization with movement (MWM)	Group A receiving Mulligan MWM joint mobilization
Kaltenborn mobilization group	Heating pad	Group B receiving Kaltenborn Joint mobilization
Kaltenborn mobilization group	Resistance Training exercise	Group B receiving Kaltenborn Joint mobilization
Kaltenborn mobilization group	Transcutaneous electrical nerve stimulation(TENS)	Group B receiving Kaltenborn Joint mobilization

Primary Outcome Measures

Name	Time	Method
knee pain	2 weeks	knee pain will be measured using visual analogue scale (VAS) from 0-100mm.A higher score on VAS indicated greater pain.
Isometeric Muscle Strength	2 weeks	Isometeric Muscle Strength will be quantified using dynamometer. A higher score on dynamometer signifies greater muscle strength and good prognosis.
Knee range of motion	2 weeks	knee range of motion will be measured using a goniometer. A higher ROM signifies positive outcome.
Gait velocity	2 weeks	Gait analysis will be done to analyze gait velocity. A greater gait velocity signifies positive outcome and prognosis.
Functional disability	2 weeks	knee functional disability will be assessed using Knee Osteoarthritis and Outcome Score(KOOS) with a score ranging from 0-100. A lower score on KOOS signifies greater functional disability
Stride length	2 weeks	Gait analysis will be done to analyze stride length. A greater stride length signifies positive outcome and prognosis.
Functional Capacity	2 weeks	5 repetition sit to stand test will be used to determine knee related functional capacity which will be quantified in terms of time. A smaller time will denote greater functional capacity.
Walking related performance fatigability	2 weeks	walking related performance fatigability will be measured using 6 minute walk test. Greater fatigibility indicates poorer outcome.

Trial Locations

Locations (1)

Foundation University Islamabad; 🇵🇰 Islamabad, Pakistan