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Clinical Trials/NCT02984345
NCT02984345CompletedNot Applicable

Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?

University of Exeter1 site in 1 country20 target enrollmentStarted: January 26, 2017Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
20
Locations
1
Primary Endpoint
Muscle fractional synthetic rate (muscle protein synthesis)

Study Overview

Brief Summary

The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Basic Science
Masking
Single (Investigator)

Eligibility Criteria

Ages
18 Years to 40 Years (Adult)
Sex
Male
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •BMI between 18 and 30 -

Exclusion Criteria

  • •Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
  • •Any diagnosed cardiovascular disease or hypertension.
  • •Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
  • •Chronic use of any prescribed or over the counter pharmaceuticals.
  • •A personal or family history of epilepsy, seizures or schizophrenia.
  • •Anyone with previous motor disorders.
  • •An allergy to mycoprotein / Quorn, penicillin, or milk.

Arms & Interventions

Mycoprotein beverage

Active Comparator

Intervention: Mycoprotein beverage (Other)

Milk protein beverage

Placebo Comparator

Intervention: Milk protein beverage (Other)

Outcomes

Primary Outcomes

Muscle fractional synthetic rate (muscle protein synthesis)

Time Frame: 7.5 hours

Secondary Outcomes

  • Plasma amino acid concentration(7.5 hours)
  • Serum insulin concentration(7.5 hours)
  • Molecular markers of muscle anabolism(7.5 hours)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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