NCT02984345CompletedNot Applicable
Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle?
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Exeter
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Muscle fractional synthetic rate (muscle protein synthesis)
Study Overview
Brief Summary
The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •BMI between 18 and 30 -
Exclusion Criteria
- •Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
- •Any diagnosed cardiovascular disease or hypertension.
- •Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
- •Chronic use of any prescribed or over the counter pharmaceuticals.
- •A personal or family history of epilepsy, seizures or schizophrenia.
- •Anyone with previous motor disorders.
- •An allergy to mycoprotein / Quorn, penicillin, or milk.
Arms & Interventions
Mycoprotein beverage
Active Comparator
Intervention: Mycoprotein beverage (Other)
Milk protein beverage
Placebo Comparator
Intervention: Milk protein beverage (Other)
Outcomes
Primary Outcomes
Muscle fractional synthetic rate (muscle protein synthesis)
Time Frame: 7.5 hours
Secondary Outcomes
- Plasma amino acid concentration(7.5 hours)
- Serum insulin concentration(7.5 hours)
- Molecular markers of muscle anabolism(7.5 hours)
Investigators
Study Sites (1)
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