CTRI/2023/11/059998Not yet recruitingNot Applicable
A descriptive study to assess the effects of different positive end expiratory pressure (PEEP) levels for evaluation of improvement in Gas exchange in Patients undergoing One Lung Ventilation in thoracic surgeries
Sawai Maan Singh Medical college and hospital1 site in 1 country50 target enrollmentStarted: December 20, 2023Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- To see the effect of various PEEP levels on PaO2/FiO2 ratio by ABG analysis
Study Overview
Brief Summary
Our aim is to evaluate the effect of various PEEP(positive end expiratory pressure) levels on PaO2 (gas exchange) in one lung ventilation in patients undergoing thoracic surgery under general anesthesia.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 90.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •) Pt. willing to give written and Informed consent.
- •Age >18yrs 3) Patient undergoing Elective thoracic Surgery.
- •ASA Grade- II and III 5) OLV lasting ≥ 60mins.
Exclusion Criteria
- •lung reduction surgery Pneumonectomy patients with severe COPD with preoperative forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio, expressed as a percentage (FEV1/FVC%) < 60% presence of large bullae, pleural diseases and/or acute or chronic.
- •uncompensated cardiac disease.
- •ASA Grade –IV.
Outcomes
Primary Outcomes
To see the effect of various PEEP levels on PaO2/FiO2 ratio by ABG analysis
Time Frame: 45minutes
Secondary Outcomes
- 1. Hemodynamic variation like Heart Rate, Systolic BP, Diastolic BP.(2.Various complications)
Investigators
Study Sites (1)
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