Overactive Bladder (OAB) Drink Advice Study
Not Applicable
Withdrawn
- Conditions
- Overactive Bladder Syndrome
- Interventions
- Dietary Supplement: water
- Registration Number
- NCT00982241
- Lead Sponsor
- Radboud University Medical Center
- Brief Summary
The researchers want to investigate how fluid intake influences the symptoms of OAB. The researchers will recruit 45 patients with OAB and randomize them (blind) in 3 groups (low/normal/high fluid intake). Patients will follow this drink pattern for 2-5 days, while filling in an standard micturation diary for 2 days. This micturation diary is coupled to: collection of multiple urine samples, urine pH measurements, and a Perception of Intensity of Urgency Scale (PPIUS) scoring table. All this is collected by the patients themselves. Urine samples will be analysed for osmolality by the clinical chemistry department.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- OAB patients
Exclusion Criteria
- benign prostatic hyperplasia
- neurogenic detrusor overactivity
- urine tract infection
- anticholinergics
- intravesical botulin toxin
- cardiac failure
- renal insufficiency
- sacral neurostimulation
- percutaneous neurostimulation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description high fluid intake water 2400 ml/day (+/- 300 ml )for 2,5 days low fluid intake water fluid intake 900 ml/day (+/- 300ml) for 2,5 days normal fluid intake water 1500 ml /day (+/- 300 ml) for 2,5 days
- Primary Outcome Measures
Name Time Method PPIUS urge-score 2 days urine osmolality 2 days
- Secondary Outcome Measures
Name Time Method PPIUS urge score 2 days urine pH 2 days
Trial Locations
- Locations (1)
Dept. of Urology, Radboud University Nijmegen Medical Centre
🇳🇱Nijmegen, Gelderland, Netherlands