The Incidence, Risk Factors, and Effects of Constipation in Critical Patients

Completed

• Conditions: Constipation

• Registration Number: NCT05683743
• Lead Sponsor: Abant Izzet Baysal University

Brief Summary

This study aimed to investigate the early, late, and total constipation frequency, related factors, and their effects on the hospitalization day, gastric residual volume, vomiting, distension, and diarrhea, the feeding type, white blood cells, and C-Reactive Protein levels, and body temperature.

Detailed Description

Constipation is one of the most encountered nursing problems in intensive care unit patients.

Constipation is an important issue, especially in intensive care patients, requiring careful discussion since it has negative effects as well as high incidence and excessive risk factors. Furthermore, untreated constipation in these patients delays enteral feeding prolonging the time of weaning from the mechanical ventilator, which consequently increases the duration of stay in the intensive care unit. Additionally, it involves complications such as distention, nausea-vomiting, an increase in bacterial infection rate, high morbidity, and mortality. Therefore, the definitions, risks, and effects of constipation, especially early and late constipation, in critically ill patients should be determined for evidence-based interventions. However, studies on the subject are limited.

Study Timeline

• Study Start: 2018-12-01
• Primary Completion: 2019-05-05
• Study Completion: 2019-07-22
• Status Verified: 2022-12
• Study First Submitted: 2022-12-16
• Study First Submitted QC: 2022-12-27
• Last Update Submitted: 2022-12-27
• Study First Posted: 2023-01-13
• Last Update Posted: 2023-01-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

• >18 years
• Not abdominal surgery
• Not stoma
• Not constipation during admission
• Not intraperitoneal infection
• Not had a recent colonoscopy -> 5 hospitalization days

Exclusion Criteria

• Having prolonged constipation and complications (such as decreased bowel sounds, and excessive distension)
• Order for regular laxatives or enemas
• Not meet inclusion criteria during follow-up

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The frequency of total constipation, early-type constipation and late-type constipation	Through study completion, an average of five months	During the study, patients in the intensive care unit with no bowel movements for four days were accepted as constipated. The ones without defecation for five days were evaluated in the early type constipation group, while the patients without defecation for six days or more were evaluated in the late-type constipation group.

Secondary Outcome Measures

Name	Time	Method
the amount of gastric residual volume	Through study completion, an avarage of five months	the amount of gastric residual volume in ml/cc
developing vomiting	Through study completion, an average of five months	developing vomiting as numbers (how many times?)
Level of white blood cells	Through study completion, an average of five months	level of white blood cells (WBC) in mcL
body temperature	Through study completion, an average of five months	body temperature in celsius
he duration of stay in the intensive care unit	Through study completion, an average of five months	the duration of stay in the intensive care unit as days (how many days?)

Trial Locations

Locations (1)

Bolu Izzet Baysal State Hospital, Anesthesia Intensive Care Unit; 🇹🇷 Bolu, Merkez, Turkey