Evaluation of the efficacy of a newly developed endotrachel tube
- Conditions
- endotracheal tube, tracheal sealing, double cuff, ventilator-associated pneumonia, prevention
- Registration Number
- NL-OMON29558
- Lead Sponsor
- niversity Hospital Brussels
- Brief Summary
1.SUYS E, NIEBOER K, STIERS W, DE REGT J, HUYGHENS L, SPAPEN H. Intermittent subglottic secretion drainage may cause tracheal damage in patients with few oropharyngeal secretions. Intensive Crit Care Nurs 2013, 29; 317-320. 2.SPAPEN H, SUYS E, NIEBOER K, STIERS W, DE REGT J. Automated intermittent aspiration of subglottic secretions and tracheal mucosa damage. Minerva Anesthesiol 2012; 79:316-7. 3.SPAPEN H, MOEYERSONS W, STIERS W, DESMET G, SUYS E. Condensation of humidified air in the inflation line of a polyurethane-cuffed endotracheal tube during mechanical ventilation causes false continuous cuff pressure readings. J Anesthesiology (submitted)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
mechanically ventilated patients > 18 years, electively intubated with the novel ETT
- patients ventilated for < 24h
- refusing informed consent
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method If on any occasion a blue spot is observed on the trachel mucosa caudal to the tube’s tip, leakage will be confirmed and the experiment ended.
- Secondary Outcome Measures
Name Time Method Throughout the experiment, following items are carefully and continuously evaluated: tube localization in the trachea (standard chest X-ray, fibroscopy), interaction with ventilation and humidification (monitoring of in- and expiratory tidal volume and airway pressures), effect of common manipulations (tracheal aspiration, transport, airway care, disconnection of ventilator, eventual weaning,…)