Clinical study of Yiqi Tongluo Xiezhuo recipe in the treatment of chronic Renal failure (Qi deficiency and Blood stasis and damp-Heat Syndrome)
- Conditions
- Chronic renal failure
- Registration Number
- ITMCTR2200006776
- Lead Sponsor
- Dongzhimen Hospital, Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) meet the diagnostic criteria of CKD III-V in the 2012 KIDIGO guidelines, and effectively control the reversible factors that may lead to the aggravation or progression of the disease, such as infection, electrolyte disturbance, hypertension, hyperglycemia, etc.; (2) meet the diagnostic criteria of TCM syndrome of qi deficiency and blood stasis and damp-heat syndrome; (3) 18-75 years old; (4) voluntary subjects who understand and sign the informed consent form
(1) secondary chronic renal insufficiency caused by systemic lupus erythematosus; (2) patients who have received or are undergoing dialysis; renal transplant patients (3) with severe primary diseases of the heart, liver, brain, blood and other organs or systems, or with consumptive diseases such as tumors, hyperthyroidism, severe inflammation, etc. (4) those who have participated in clinical trials within 3 months or have used glucocorticoids, immunosuppressive drugs, Tripterygium wilfordii preparations, or are receiving the above treatment; (5) 24-hour urinary protein = 3.0g; serum albumin = 25g / L; (6) pregnant or lactating women: (7) those who are known to be allergic to drug ingredients; (8) the range of GFR fluctuation = 30% in the first 3 months of the group.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glomerular filtration rate;
- Secondary Outcome Measures
Name Time Method Serum albumin;Hemoglobin;Blood urea nitrogen;Four items of blood lipid;TCM syndrome integral;Serum creatinine;Urinary protein / creatinine ratio;24-hour urinary protein quantification;