Investigating the impact of animal-derived milk on pro- and anti-inflammatory immune responses in healthy subjects
Not Applicable
- Conditions
- Impact of diet on the immune system
- Registration Number
- DRKS00034603
- Lead Sponsor
- niversitätsklinikum Bonn
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
none
Exclusion Criteria
- autoimmune or neurological diseases
- proven gluten intolerance
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method • Evidence of milk-reactive antibodies in the peripheral blood<br>• Evidence of an effect of cow's milk consumption on pro- and anti-inflammatory immune responses depending on the existence of a milk-specific immune response when entering the study
- Secondary Outcome Measures
Name Time Method • Milk-specific antibody titers before and after cow's milk consumption<br>• Change in the percentage distribution of pro and anti-inflammatory immune cell populations before and after cow's milk consumption<br>• Change of the permeability of the intestinal barrier before and after cow's milk consumption<br>• Change of microbiome composition before and after cow's milk consumption