Comparison of the effect of verapamil with corticosteroids in the treatment of keloids

Phase 2

• Conditions: Keloid.; Hypertrophic scar

• Registration Number: IRCT2016010525871N1
• Lead Sponsor: Vice chancellor fpr research of Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

age over 18 years; two or more hypertrophic scars or keloids; total area less than 10 square centimeters; no previous treatment; scars under 5 years duration
Exclusion criteria: Facial keloids; infection or ulcer, in or near the scar; pregnancy and lactation; patients with systemic illness like diabetes mellitus, mental disorder, cancer and cardiac disease; dark pigmented skin

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scar pigmentation. Timepoint: Before intervention, every 3 weeks for a period of 6 months, 3 months after the end of the intervention. Method of measurement: Observation and scoring based on Vancouver Scar Scale.;Height of the scar. Timepoint: Before intervention, every 3 weeks for a period of 6 months, 3 months after the end of the intervention. Method of measurement: Using ruler and scoring based on Vancouver Scar Scale.;Vascularity. Timepoint: Before intervention, every 3 weeks for a period of 6 months, 3 months after the end of the intervention. Method of measurement: visual inspection and the rate of refill after blanching and scoring based on Vancouver Scar Scale.;Scar pliability. Timepoint: Before intervention, every 3 weeks for a period of 6 months, 3 months after the end of the intervention. Method of measurement: Palpation and scoring based on Vancouver Scar Scale.

Secondary Outcome Measures

Name	Time	Method
Patient's satisfaction. Timepoint: At the end of the study. Method of measurement: Asking the patients about any alternation in side effects of the keloids e.g. pain and pruritus.