Comparing the effects of intralesional Meglumine Antimonate injection alone and intralesional Meglumine Antimonate injection plus local barberry root extract in cutaneous leishmaniosis treatment
Phase 2
- Conditions
- cutaneous leishmaniasis.Cutaneous leishmaniasis
- Registration Number
- IRCT2017060117756N16
- Lead Sponsor
- Vice-chancellery for Research of Mashhad University of Medicla Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Positive direct smear in terms of Leishman-Donovan body; time passed less than 6 months from legion onset; no other treatment received for leishmaniasis during the last three months; informed consent for participation; lesion located is in upper limbs or the face.
Exclusion criteria: Allergy to Meglumine (severe local reactions or anaphylaxis) or topical compounds used; irregular visits; incidence of secondary infection of the lesions based on clinical features and the therapist’s judgment ; presence of systemic treatment indications for cutaneous leishmaniosis including lesions on joints, number of lesions more than or equal to 5, lesion size more than or equal to 5 cm.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Enduration. Timepoint: On the last injection and 6 weeks later. Method of measurement: ruler.
- Secondary Outcome Measures
Name Time Method