Analysis of the Prognosis and Clinical Course in Patients With Chronic Respiratory Failure Receiving Domiciliary NPPV
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 56
- Locations
- 11
- Primary Endpoint
- Prognosis/Mortality
Study Overview
Brief Summary
The purposes of the present study are (1) to analyze baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors, and (3) to examine longitudinal clinical course in patients with chronic respiratory failure receiving domiciliary NPPV.
Detailed Description
Limited data are available about the prognosis and its predictive factors in patients with chronic respiratory failure receiving domiciliary NPPV. In addition, their health status, psychological status and sleep quality seem to be highly disturbed due to severe respiratory insufficiency. Therefore, in the present study, we aim to examine (1) contributive factors to health status based on baseline data, (2) whether patient reported measurements such as health status, dyspnea and psychological status would predict patient's future outcomes, and (3) how they would change for 3 years as compared to physiological measurements.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with chronic respiratory failure receiving domiciliary NPPV for more than 3 months
Exclusion Criteria
- •Uncontrolled severe comorbidities
- •Patients with tracheotomy.
Outcomes
Primary Outcomes
Prognosis/Mortality
Time Frame: 3 years
Secondary Outcomes
- Psychological status(At entry and every year for 3 years)
- Pulmonary function(At entry and every year for 3 years)
- Arterial blood gas(At entry and every year for 3 years)
- Dyspnea(At entry and every year for 3 years)
- Health status(At entry and every year for 3 years)
- 6 minute walking tests(At entry and every year for 3 years)
- Sleep quality(At entry and every year for 3 years)
Investigators
Toru Oga
Respiratory Care and Sleep Control Medicine, Kyoto University, Graduate School of Medicine
Kyoto University, Graduate School of Medicine