Characterising gaze patterns during driving among people who use methamphetamine

Not Applicable

• Conditions: Substance use; Injuries and Accidents - Other injuries and accidents; Mental Health - Addiction

• Registration Number: ACTRN12623000191695
• Lead Sponsor: Swinburne University of Technology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-02-23
• Last Update Posted: 27 February 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1.Healthy Controls
•Male and female participants aged 21-60 years.
•Willing and able to provide written informed consent.
•Understands and is willing and able to comply with all study procedures.
•Fluent in written and spoken English.
•Normal vision or corrected with contact lenses.
•Currently hold a (full) drivers’ licence (no ‘P-platers’) and are active drivers (at least once/week), with at least three years of driving experience.
•No history of use of illicit amphetamine substances [amphetamine, methamphetamine, methylenedioxymethamphetamine (MDMA)]
•No use of other illicit substances or recreational (off-target) use of prescription medication either in past 12 months
•Absence of lifetime chronic/binge drug use (self-report)
•MMSE score greater than or equal to 23 (normal cognitive function)
•Willing to abstain from the following prior to their scheduled visit:
oNo caffeine-containing products within 12 hours prior to testing
oNo alcohol within 12 hours prior to testing
oNo medication for at least 1 week prior to testing (except for prophylactic antibiotics, contraceptive pill, or other routine medications to treat benign conditions, such as antibiotics to treat acne)
oNo illicit substance use for one week prior to, and for the duration of the trial.

2.People who use methamphetamine
•Male and female participants aged 21-60 years.
•Willing and able to provide written informed consent.
•Understands and is willing and able to comply with all study procedures.
•Fluent in written and spoken English.
•Normal vision or corrected with contact lenses.
•Currently hold a (full) drivers’ licence (no ‘P-platers’) and are active drivers (at least once/week), with at least three years of driving experience.
•Self-reported current, ongoing use of methamphetamine (greater than or equal to 1/week for the past 6 weeks)
•Mini Mental State Exam (MMSE) score greater than or equal to 23 (normal cognitive function)
•Physician diagnosed current methamphetamine dependence (DSM-5 or equivalent)
•Does not meet other DSM substance-use criteria concurrently, except for nicotine or cannabis dependence (physician-confirmed).
•Willing to abstain from the following prior to their scheduled visit:
oNo methamphetamine for 12 hours prior to testing (self-report)
oNo alcohol within 12 hours prior to testing

Exclusion Criteria

1.Healthy Controls
•Unable to understand or comply with testing procedures.
•Inability to speak or read English.
•Taking any form of medication within one week of admission (except for prophylactic antibiotics, contraceptive pill, or other routine medications to treat benign conditions, such as antibiotics to treat acne) and agree not to take any medication throughout the study
•Unable to participate in scheduled visit, treatment plan, tests, and other study procedures according to the protocol.
•Currently under administrative or legal supervision.

2.People who use methamphetamine
•Unable to understand or comply with testing procedures.
•Inability to speak or read English.
•Unable to participate in scheduled visit, treatment plan, tests and other study procedures according to the protocol (e.g., unable to abstain from methamphetamine for 12 hours prior to study session).
•Currently under administrative or legal supervision.

Study & Design

• Study Type: Observational
• Study Design: Not specified