Investigation of the Efficacy of Pre-operative Endocrine Therapy with Toremifene cirate and Exemestane for Postmenopausal Breast Cancer Patients
Phase 2
Recruiting
- Conditions
- Hormone-receptor positive postmenopausal breast cancer patients
- Registration Number
- JPRN-UMIN000007014
- Lead Sponsor
- Japan Breast Cancer Research Network
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 25
Inclusion Criteria
Not provided
Exclusion Criteria
1. Inflammatory breast cancer 2. Active double cancer 3. Severe heart diseases including myocardial infarction, cardiac insufficiency or patients who have a medical history in these diseases 4. Medical history in deep vein thrombosis 5. Cirrhosis 6. Fever with more than 38 degree 7. Patients who have bleeding tendency 8. Patients who are judged as ineligible for the study enrollment by investigators
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical response rate
- Secondary Outcome Measures
Name Time Method Histological therapeutic effect Rate of breast-conserving surgery Safety Change of Ki 6 7, Change of ER/PgR/HER2