The effect of dexmedetomidine on pain, nausea and vomiting following orthognathic surgery

Phase 3

Recruiting

• Conditions: Condition 1: Acute pain. Condition 2: Nausea and vomiting.; Acute pain, not elsewhere classified; Nausea and vomiting; G89.1

• Registration Number: IRCT20150613022697N9
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients between the ages of 18 and 40
Patients with skeletal class 3 deformity who are candidates for bimaxillary orthodontic surgery (maxillary advancement using Lefort 1 osteotomy and mandibular setback surgery by bilateral sagittal split osteotomy (BSSO))
Patients with a Body Mass Index of less than 30 kg / m2
Patients who have completed the informed consent

Exclusion Criteria

Patients with a history of drug allergy
Patients with a history of Motion Sickness
Patients with a history of addiction or psychological problems
Patients with a history of hypotension and bradycardia
Patients with upper gastrointestinal problems such as gastric ulcer, reflux, pyloric stenosis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain degree. Timepoint: 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: Visual analogue scale (VAS) for pain.;Presence or absence of nausea. Timepoint: Immediately after recovery and 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: scoring (0=non, 1=nausea).;Presence or absence of vomiting. Timepoint: Immediately after recovery and 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: scoring (0=non, 1=vomiting, 2=vomiting >2 times).