A trial to compare efficiency of a drug used to reduce blood loss in surgical procedures when given through veins at different timings before, during and after surgery.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Total blood loss in total knee replacement.
- Registration Number
- CTRI/2018/05/013588
- Lead Sponsor
- SUNSHINE HOSPITALS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
Informed consent
Those undergoing primary unilateral knee replacement.
Exclusion Criteria
Abnormal PT/APTT/INR or coagulopathic diseases
Undergoing B/L TKR / revision surgeries of any cause
Past h/o thromboembolic events
Treated with Aspirin or any anti-platelets within 1 week prior to the surgery
TKR done for secondary OA (rheumatoid arthritis, post traumatic arthritis)
History of reported allergy to tranexamic acid
Pre operative hemoglobin <8gm/dl
Chronic renal insufficiency
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method