Study on the mechanism of Qingchangxiaopi Decoction and UC large intestine damp-heat syndrome from the activation of LPDC through TLR5-IRF4 pathway to mediate intestinal inflammatio
- Conditions
- lcerative Colitis
- Registration Number
- ITMCTR2200005909
- Lead Sponsor
- Dongguan Hospital of Guangzhou University of Chinese Medinine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- Not specified
?The healthy subjects were inquired about medical history and physical examination, excluded cardiovascular and cerebrovascular diseases, diabetes, hypertension, hyperlipidemia and other medical history, and excluded intestinal organic diseases.
?UC patients who meet the diagnostic criteria;
?Meet the criteria for UC in the light to moderate activity period;
?Those who signed the informed consent.
?Patients with severe heart, liver, kidney and other major organ diseases, hematopoietic system, nervous system or mental diseases;
?Patients with serious complications such as local stricture, toxic megacolon, intestinal obstruction, colon cancer, rectal cancer, intestinal perforation and anal disease;
?Reluctance to sign informed consent and collaborators.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method