A Drug Named Dexmedetomidine Will Be Used In Inhalational Form Into Your Breathing System To Blunt The Stress Response Which Occurs While Putting A Tube Through The Mouth Into The Breathing System Before Surgery
- Conditions
- Measurement and Monitoring,
- Registration Number
- CTRI/2022/10/046174
- Lead Sponsor
- VMMC AND SAFDARJUNG HOSPITAL
- Brief Summary
Adult Patients Undergoing Elective Surgeries will be Nebulized with Dexmedetomidine of dose 0.6 mcg/kg preoperatively to blunt the stress response to endotracheal intubation and hemodynamic parameters such as heart rate, blood pressure will be noted at various time intervals.
Also baseline serum cortisol will be estimated and also serum cortisol levels will be noted 10minutes after intubation to evaluate the stress response to intubation
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 120
Adults of age group from 18 to 65 years undergoing elective surgeries ASA grade 1 patients.
Age group less than 18 years and more than 65 years History of hypersensitivity to Dexmedetomidine Pregnancy Patient on psychiatric medications, on steroid therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in Haemodynamic parameters such as heart rate, Blood pressure,Mean arterial pressure.To determine cortisol levels 10minutes post intubation Measurement of heart rate, Blood pressure, Mean arterial pressure at 0,3,5,10 minutes after intubation. Measurement of cortisol levels at 10 minutes after intubation
- Secondary Outcome Measures
Name Time Method To determine cortisol levels 10 minutes post intubation Measurement of cortisol levels at 10 minutes after intubation
Trial Locations
- Locations (1)
VMMC AND SAFDARJUNG HOSPITAL NEW DELHI
🇮🇳Delhi, DELHI, India
VMMC AND SAFDARJUNG HOSPITAL NEW DELHI🇮🇳Delhi, DELHI, IndiaDr Krishna sPrincipal investigator9986971935Krishnasampath273@gmail.com