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Macintosh Blade Size During Laryngoscopy for Endotracheal Intubation. A Prospective Observational Study.

Conditions
Endotracheal Intubation
Interventions
Device: Direct laryngoscopy for endotracheal intubation
Registration Number
NCT05059067
Lead Sponsor
University Hospital, Clermont-Ferrand
Brief Summary

Endotracheal intubation is a frequent procedure in the operating room, in intensive care units and in emergency medicine (in- or out-of-hospital) but optimal Macintosh blade size remains unknown to date.

Detailed Description

Endotracheal intubation is an extremely frequent procedure in the operating room, in intensive care units and in emergency medicine (in- or out-of-hospital). Apart from special cases of foreseen difficult programmed intubation, direct laryngoscopy remains the most frequently used technique. It requires the use of a handle (short or long), which serves as a light source on which is adapted a Macintosh curved blade, metallic or plastic, single or multiple use. The choice of blade size is based on the experience of the physician. Most often, in adult settings, size 3 or 4 blades are used. The very spartan literature on the subject and the current recommendations do not provide any information on the choice of blade size. We therefore wish to evaluate these practices in terms of success of the first laryngoscopy, Cormack-Lehane and POGO (percentage of glottic opening visualized) scores, the need to use an alternative technique or a second operator. The results will be analyzed with regard as a function and experience of the person performing the laryngoscopy, as well as the setting (urgent or scheduled). These data are usually collected during the performance of an endotracheal intubation whatever the circumstances: operating room, intensive care unit and emergency department (in-hospital) and in the SAMU-SMUR (pre-hospiatl medical service) at Clermont-Ferrand University Hospital.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
1500
Inclusion Criteria
  • Patients must be admitted in an operative room, an intensive care unit (ICU) or an emergency department and require mechanical ventilation through an orotracheal tube.
  • Adult (age ≥ 18 years)
  • Subjects must be covered by public health insurance
  • Written informed consent from the patient or proxy (if present) before inclusion or once possible when patient has been included in a context of emergency.
Exclusion Criteria
  • Anticipated difficult intubation requiring videolaryngoscopy
  • Nasotracheal intubation
  • Refusal of study participation or to pursue the study by the patient
  • Absence of coverage by the French statutory healthcare insurance system
  • Protected person

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Macintosh blade size 3Direct laryngoscopy for endotracheal intubationPatients intubated using Macintosh blade size 3
Macintosh blade size 4Direct laryngoscopy for endotracheal intubationPatients intubated using Macintosh blade size 4
Primary Outcome Measures
NameTimeMethod
Number of patients with successful first-pass orotracheal intubationAt intubation

The proportion of patients with successful first-pass orotracheal intubation

Secondary Outcome Measures
NameTimeMethod
Additional second operatorDuring intubation

Rate of need for a second operator

Severe complications related to intubation_deathAt intubation

Rate of death during intubation

Cormack LehaneDuring intubation

Rate of Cormack-Lehane grade of glottic view

Difficulty of intubationDuring intubation

Rate of operator-assessed difficulty of intubation

Severe complications related to intubation_hypoxemiaAt intubation

Rate of severe hypoxemia defined by lowest oxygen saturation (SpO2) \< 80 %

Moderate complications related to intubation_difficult intubationAt intubation

Rate of difficult intubation

Moderate complications related to intubation_arrythmiaAt intubation

Rate of severe ventricular or supraventricular arrhythmia requiring intervention

Severe complications related to intubation_severe collapseAt intubation

Rate of cardiovascular collapse, defined as systolic blood pressure less than 65 mm Hg recorded at least once or less than 90 mm Hg lasting 30 minutes despite 500-1,000 ml of fluid loading (crystalloids solutions) or requiring introduction or increasing doses by more than 30% of vasoactive support

Severe complications related to intubation_cardiac arrestAt intubation

Rate of cardiac arrest

Moderate complications related to intubation_dental injuriesAt intubation

Rate of dental injuries

POGO (percentage of glottic opening)During intubation

Rate of POGO grade of glottic view

Moderate complications related to intubation_oesophageal intubationAt intubation

Rate of oesophageal intubation

Moderate complications related to intubation_agitationAt intubation

Rate of agitation

Moderate complications related to intubation_aspirationAt intubation

Rate of pulmonary aspiration

Additional airway equipmentDuring intubation

Rate of need for additional airway equipment (video laryngoscope, bougie, stylet, fibroscope, cricothyrotomy)

Trial Locations

Locations (1)

CHU

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Clermont-Ferrand, France

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