The effect of dexmedetomidine on the control of the brains blood flow in children, as assessed by doppler ultrasound of the blood vessels in the brain when under anaesthesia
Phase 4
- Registration Number
- CTRI/2024/05/066764
- Lead Sponsor
- Dr Mathew George
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing spine surgery under Motor Evoked Potential monitoring
Exclusion Criteria
1)Age <3 months and >14years
2)Patients with known allergy to any of the drugs used in the study (general anaesthetics, dexmedetomidine)
3)Disturbed intracranial dynamics that may affect TCD readings –untreated hydrocephalus, craniosynostosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transient Hyperaemic Response Ratio (THRR) measured from the right middle cerebral arteryTimepoint: measurements of THRR will be made 10 minutues after induction of anaesthesia, before the commencement of the surgery
- Secondary Outcome Measures
Name Time Method Strength of Autoregulation(SA) will be calculated as a secondary outcomeTimepoint: Measurements will be taken 10 minutes after the induction of anaesthesia, & before the commencement of surgery