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Effect of a herbal medicine combinations in the treatment of chronic sinusitis

Phase 3
Conditions
Chronic sinusitis.
J32Chronic sinusitis Incl.: abscess, empyema, infection, suppuration (chronic) of sinus (accessory)(nasal
Registration Number
IRCT2015112425217N1
Lead Sponsor
Vice Chancellery for Research of Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
52
Inclusion Criteria

Two criteria of the main criteria (including: nasal obstruction or congestion; anterior or posterior nasal secretion; facial pain or pressure; and reduction or loss of smell) or one major criterion and two minor criteria (including dental pain; cough; pain; pressure or fullness feel in ears; fatigue; headache or halitosis) for more than 12 weeks during the past 12 months.
Exclusion criteria: Chronic sinusitis along with acute bacterial infections of the respiratory tract; Chronic sinusitis along with anatomical obstructions requiring surgery; Sensitivity or contraindication to the drug components; Pregnancy; Immunodeficiency; The presence of high blood pressure (hypertension history or blood pressure on admission greater than 140/90 mm Hg)

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Symptoms of chronic sinusitis. Timepoint: Baseline and sixth, eighth and twelfth week after intervention. Method of measurement: SNOT22 Questionnaire.
Secondary Outcome Measures
NameTimeMethod
Paranasal sinuses status. Timepoint: Before the intervention and twelve weeks after beginning intervention. Method of measurement: Lund-Mackey Score.;Symptoms of cold Coryza (Zokam) and Catarrh (Nazlah). Timepoint: Before the intervention and twelve weeks after intervention beginning. Method of measurement: cold Coryza (Zokam) and Catarrh (Nazlah) questionnaire.
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