Mometasone irrigation in the treatment of chronic rhinosinusitis

Phase 4

Recruiting

• Conditions: Chronic rhinosinusitis; Inflammatory and Immune System - Other inflammatory or immune system disorders

• Registration Number: ACTRN12612000866808
• Lead Sponsor: A/Prof Richard Harvey

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-08-16
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Any CRS patient undergoing endoscopic sinus surgery, and where CRS, with or without nasal polyps, is defined as the presence of two or more symptoms for > 12 weeks, one of which should be:
either nasal blockage/obstruction/congestion or nasal discharge
(anterior/posterior nasal drip):
+/- facial pain/pressure;
+/- reduction or loss of smell;
AND endoscopic or radiographic evidence of mucosal inflammation

2. Willingness to give written informed consent and willingness to participate in and comply with the study.

Exclusion Criteria

1. Patients under the age of 18
2. Pregnant women
3. History of sensitivity to Mometasone.
4. Patients unable to give informed consent because of age, mental illness, dementia, communication difficulties

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the effect on symptom control in CRS patients in the post-operative management, assessed using Visual Analogue Scale, SF36v2 (General quality of life questionnaire), and SNOT22 (disease-specific quality of life questionnaire).[Pre-operative baseline, then at 6 wks, 3 months, 6 and 12 months post-operatively];To compare objective endoscopic and radiologic scores in the same patient cohort[Pre-operative baseline, then at 6 wks, 3 months, 6 and 12 months post-operatively (radiologic at baseline and 12 months only)]