NCT01805193已完成不适用
Validation of Computed Tomography Myocardial Perfusion Imaging Using Quantification of Myocardial Blood Flow by Positron Emission Tomography With 15O-water
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Myocardial blood flow
研究概览
简要总结
Coronary heart disease is a very common condition caused by narrowings in the blood vessel supplying the heart. the investigators are studying new tests to diagnose heart disease. In this study the investigators plan to investigate a special scan called a PET/CT (Positron emission tomography/computed tomography) and a new type of CT (Computed tomography) scan to tell us about the flow of blood to the heart muscle.
详细描述
Participants will undergo PET/CT with oxygen-15 labelled water and computed tomography myocardial perfusion imaging.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •suspected coronary artery disease
排除标准
- •inability or unwillingness to undergo CT or PET imaging
- •renal failure (serum creatinine >200 um/L or eGFR <30 ml/min)
- •hepatic failure
- •allergy to iodinated contrast
- •pregnancy
- •contraindication to adenosine
- •inability to give informed consent
- •atrial fibrillation with a fast ventricular rate (>70 beats per minute)
结局指标
主要结局
Myocardial blood flow
时间窗: 1 month
Myocardial blood flow ( ml/g/min) measured by oxygen-15 water positron emission tomography
次要结局
- Myocardial perfusion(1 month)
- Fractional flow reserve(1 month)
研究者
研究点 (1)
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