Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT
研究概览
简要总结
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as direct regulators of atherosclerosis. Therefore, the investigators examine the correlation of various metabolic risk factors including adipokines and hepatokines with coronary atherosclerosis measured by coronary MDCT in apparently healthy people.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center.
- •age > 20 years
排除标准
- •History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
- •Stage 2 hypertension
- •Severe renal or hepatic disease
结局指标
主要结局
relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT
时间窗: 3month
to examine the correlation of serum concentration of various adipokine such as adiponectin, resistin, A-FABP with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score
次要结局
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT(3months)
- the correlation of various inflammatory markers with coronary atherosclerosis(3months)