Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Atherosclerosis
- Sponsor
- Korea University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as direct regulators of atherosclerosis. Therefore, the investigators examine the correlation of various metabolic risk factors including adipokines and hepatokines with coronary atherosclerosis measured by coronary MDCT in apparently healthy people.
Investigators
Kyung Mook Choi
Professor
Korea University
Eligibility Criteria
Inclusion Criteria
- •Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center.
- •age \> 20 years
Exclusion Criteria
- •History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
- •Stage 2 hypertension
- •Severe renal or hepatic disease
Outcomes
Primary Outcomes
relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT
Time Frame: 3month
to examine the correlation of serum concentration of various adipokine such as adiponectin, resistin, A-FABP with coronary atheroslcerosis measured by MDCT as AGATSTON score, modified Gensini score
Secondary Outcomes
- relation of adipokines and hepatokines with coronary atherosclerosis measured by MDCT(3months)
- the correlation of various inflammatory markers with coronary atherosclerosis(3months)