A COMPARATIVE STUDY OF TRANSVERSUS ABDOMINIS PLANE BLOCK VERSUS QUADRATUS LUMBORUM BLOCK FOR POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING LOWER SEGMENT CAESAREAN SECTION
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- 1. To assess and compare the duration of postoperative analgesia provided by TAP and QL blocks. Duration of analgesia will be defined as the time from completion of the block to the first request for rescue analgesia. This objective helps in determining which block provides longer-lasting pain relief postoperatively.
研究概览
简要总结
In India, where cesarean section are on the rise, access to safe, effective, and affordable analgesic methods is vital. Many healthcare settings still rely heavily on systemic opioids or intrathecal morphine, which may not always be available or desirable due to their side effects, Ultrasound guided nerve blocks, TAP and QL offer reproducible, cost-effective solutions with minimal systemic effects and can be incorporated easily into postoperative protocols.
This study addresses the existing gap in the literature by directly comparing the efficacy of ultrasound guided TAP versus QL block in the postoperative pain management of LSCS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- •The inclusion criteria for this study are carefully defined to ensure a homogeneous study population, minimize confounding variables, and enhance the validity of the comparison between TAP and QL blocks for postoperative analgesia in LSCS.
- •The criteria are designed to select patients who are likely to benefit from regional anaesthesia and whose clinical characteristics align with the study’s objectives.
- •The following inclusion criteria are applied:
- •Age Range: Participants must be adult women aged 18 to 40 years.
- •It also minimizes age related physiological variations that could affect pain perception or anaesthetic response.
- •ASA Physical Status I or II: Patients are included if they are classified as ASA I (healthy individuals with no systemic disease) or ASA II (individuals with mild systemic disease that does not limit activity, controlled hypertension or mild asthma).
- •This criterion ensures that participants are generally healthy or have well managed conditions, reducing the risk of anaesthesia related complications and ensuring that pain outcomes are not confounded by severe comorbidities.
- •No History of Chronic Pain or Opioid Use: Patients with no history of chronic pain conditions (fibromyalgia, chronic pelvic pain) or long-term opioid use are included.
- •This criterion minimizes baseline differences in pain perception and opioid tolerance, which could skew the study’s pain and analgesic consumption outcomes.
- •Ability to Provide Informed Consent: Participants must be capable of understanding the study’s purpose, procedures, and risks and provide written informed consent.
- •This ensures ethical compliance and confirms that patients are willing to adhere to the study protocol, including postoperative assessments.
- •No Allergies to Local Anaesthetics: Patients with no known allergies to local anaesthetics ( 0.75 of Ropivacaine).
- •This criterion is critical to ensure the safety of the block administration and avoid adverse reactions that could confound the study results.
- •These inclusion criteria are applied during the preoperative screening process, typically conducted by the research team in collaboration with obstetricians and anaesthesiologists.
- •Patients are assessed through medical history reviews, physical examinations, and laboratory tests (if needed) to confirm eligibility.
- •The criteria are designed to create a study population that is clinically stable, representative of the typical LSCS patient, and suitable for evaluating the analgesic efficacy of TAP versus QL blocks.
- •By adhering to these inclusion criteria, the study ensures that the results are generalizable to a broad population of parturient undergoing LSCS while minimizing variables that could affect the reliability of the comparison between the two regional anaesthesia techniques.
排除标准
- 未提供
结局指标
主要结局
1. To assess and compare the duration of postoperative analgesia provided by TAP and QL blocks. Duration of analgesia will be defined as the time from completion of the block to the first request for rescue analgesia. This objective helps in determining which block provides longer-lasting pain relief postoperatively.
时间窗: 1. To assess and compare the duration of postoperative analgesia provided by TAP and QL blocks. Duration of analgesia will be defined as the time from completion of the block to the first request for rescue analgesia. This objective helps in determining which block provides longer-lasting pain relief postoperatively. | 2. To evaluate postoperative pain scores at specified intervals using the Visual Analogue Scale (VAS) Pain will be assessed using the VAS at rest and on movement at predetermined time intervals post-surgery—such as at 2, 4, 6, 12, and 24 hours. This will help establish the trajectory of pain control offered by each block. | 3. To quantify and compare the total amount of rescue analgesic consumption in the first 24 hours postoperatively. The need for additional analgesics, including non-opioid and opioid medications, will be recorded. A lower requirement would reflect a more effective block.
2. To evaluate postoperative pain scores at specified intervals using the Visual Analogue Scale (VAS) Pain will be assessed using the VAS at rest and on movement at predetermined time intervals post-surgery—such as at 2, 4, 6, 12, and 24 hours. This will help establish the trajectory of pain control offered by each block.
时间窗: 1. To assess and compare the duration of postoperative analgesia provided by TAP and QL blocks. Duration of analgesia will be defined as the time from completion of the block to the first request for rescue analgesia. This objective helps in determining which block provides longer-lasting pain relief postoperatively. | 2. To evaluate postoperative pain scores at specified intervals using the Visual Analogue Scale (VAS) Pain will be assessed using the VAS at rest and on movement at predetermined time intervals post-surgery—such as at 2, 4, 6, 12, and 24 hours. This will help establish the trajectory of pain control offered by each block. | 3. To quantify and compare the total amount of rescue analgesic consumption in the first 24 hours postoperatively. The need for additional analgesics, including non-opioid and opioid medications, will be recorded. A lower requirement would reflect a more effective block.
3. To quantify and compare the total amount of rescue analgesic consumption in the first 24 hours postoperatively. The need for additional analgesics, including non-opioid and opioid medications, will be recorded. A lower requirement would reflect a more effective block.
时间窗: 1. To assess and compare the duration of postoperative analgesia provided by TAP and QL blocks. Duration of analgesia will be defined as the time from completion of the block to the first request for rescue analgesia. This objective helps in determining which block provides longer-lasting pain relief postoperatively. | 2. To evaluate postoperative pain scores at specified intervals using the Visual Analogue Scale (VAS) Pain will be assessed using the VAS at rest and on movement at predetermined time intervals post-surgery—such as at 2, 4, 6, 12, and 24 hours. This will help establish the trajectory of pain control offered by each block. | 3. To quantify and compare the total amount of rescue analgesic consumption in the first 24 hours postoperatively. The need for additional analgesics, including non-opioid and opioid medications, will be recorded. A lower requirement would reflect a more effective block.
次要结局
- To study the influence of each block on early ambulation andreturn to normal activities postsurgery. Parameters such as time to mobilization, ability to breastfeed comfortably aNd(participation in newborn care will be noted to)
研究者
SHASHANK KUMAR SRIVASTAV
Command Hospital Air Force, Bangalore