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Clinical Trials/NCT03000699
NCT03000699
Completed
Not Applicable

Efficacy of Cognitive Bias Modification in Residential Treatment for Addiction

Centre for Addiction and Mental Health1 site in 1 country88 target enrollmentMarch 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Substance Dependence
Sponsor
Centre for Addiction and Mental Health
Enrollment
88
Locations
1
Primary Endpoint
Columbia-Suicide Severity Rating Scale, Screen Version (C-SSRS)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to determine whether computer bias modification for interpretation bias (CBM-I) is effective in the reduction of suicidal ideation in substance use disorders.

Detailed Description

Eighty-eight adult inpatients completing residential treatment in the Addictions Services at the Centre for Addiction and Mental Health (CAMH) will be randomized to receive CBM-I daily for one week, adjunct to the residential psychosocial treatment or to an assessment-only control condition. Participants will complete clinical measures consisting of interviews and questionnaires measuring suicidal ideation, hopelessness, depression, negative affect, and interpretation biases before, during and after treatment.

Registry
clinicaltrials.gov
Start Date
March 1, 2017
End Date
December 31, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Lena Quilty

Independent Scientist

Centre for Addiction and Mental Health

Eligibility Criteria

Inclusion Criteria

  • Exhibit moderate suicide risk or greater
  • Be enrolled in the Addictions Services inpatient program
  • Fluent in reading English
  • Capacity to give informed consent

Exclusion Criteria

  • A lifetime diagnosis of a psychotic or bipolar disorder
  • Significant neurological disorder or psychical illness likely to interfere with participation
  • Psychotropic medication changes within the past two weeks

Outcomes

Primary Outcomes

Columbia-Suicide Severity Rating Scale, Screen Version (C-SSRS)

Time Frame: Seven days

This scale quantifies the severity of suicidal ideation and behaviour.

Secondary Outcomes

  • Positive and Negative Affect Schedule (PANAS)(Seven days)
  • Beck Hopelessness Scale (BHS)(Seven days)
  • Beck Depression Inventory II (BDI-II)(Seven days)
  • Scrambled Sentences Tests(Seven days)

Study Sites (1)

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