What causes incontinence after robot-assisted prostate removal in men with prostate cancer?

Not Applicable

• Conditions: Incontinence following radical prostatectomy for prostate cancer; Surgery

• Registration Number: ISRCTN67297115
• Lead Sponsor: niversity of Gothenburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-01
• Last Update Posted: 20 November 2023
• Study Completion: 2028-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: Male
• Target Recruitment: 1000

Inclusion Criteria

Patients scheduled for robot-assisted laparoscopic radical prostatectomy at Sahlgrenska University Hospital

Exclusion Criteria

Pre-operative incontinence

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rethral length, position of prostate apex, position of bladder neck, position of urethra, thickness of urethra, M. levator ani and M. Pubourethralis/puborectalis and signs of fibrosis of urethra wall, assessed by MRT at baseline and 12 weeks (except for prostate apex at 12 weeks)

Secondary Outcome Measures

Name	Time	Method
<br> 1. Clinical characteristics (comorbidity, medications, BMI, smoking, IPSS, PSA, Gleason score and T-stage) assessed at baseline<br> 2. Urethra pressure profile, sphincter length, function of bladder and bladder outflow tract assessed by urodynamics at baseline and 12 weeks<br> 3. Position and movement of bladder neck and pelvic floor at relaxation and full tension of pelvic floor assessed by ultrasound at baseline and at 12 weeks.<br> 4. Steps of surgery and potential damage of structures around sphincter assessed by video recording at time of surgery<br>