Effects of vaccinium arctostaphylos fruit on cardiometabolic indices in hypertensive obese patients
- Conditions
- Condition 1: Obesity. Condition 2: Hypertension.Obesity due to excess caloriesEssential (primary) hypertension
- Registration Number
- IRCT201710302288N12
- Lead Sponsor
- Vice Chancellor for Research, Research Institute for Islamic and Complementary Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Iranian male and female hypertensive obese outpatients; patients aged 30 to 80 years; patients with body mass index between 25 kilograms per square meter and 35 kilograms per square meter; patients with systolic blood pressures between 14 and 16 mmHg; patients with diastolic blood pressures between 8 and 10 mmHg; patients taking synthetic antihypertensive drugs with 2 different mechanisms. Exclusion criteria: Patients taking other drugs effective on the blood glucose and lipid levels and body weight; patients with cardiac, renal, hepatic, hematological diseases, hypothyroidism, tachycardia, vertigo and seizure; patients with a history of gallstones or gall bladder surgery; pregnant women; women planning pregnancy; breast-feeding women.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood level of glycosylated hemoglobin. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood level of low density lipoprotein cholesterol. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Body mass index. Timepoint: Before and after 3 months of intervention. Method of measurement: Scale and tape measure.;Waist circumference. Timepoint: Before and after 3 months of intervention. Method of measurement: Tape measure.;Systolic blood pressure. Timepoint: Before and after 3 months of intervention. Method of measurement: 24-hour ambulatory blood pressure monitoring.;Diastolic blood pressure. Timepoint: Before and after 3 months of intervention. Method of measurement: 24-hour ambulatory blood pressure monitoring.
- Secondary Outcome Measures
Name Time Method Fasting blood glucose level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood total choletserol level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood triglyceride level. Timepoint: Before and after 3 months of intervention. Method of measurement: kit.;Blood high density lipoprotein cholesterlol level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood serum glutamate oxaloacetate transaminase level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood serum glutatamate pyruvate transaminase level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.;Blood creatinine level. Timepoint: Before and after 3 months of intervention. Method of measurement: Kit.