Study on efficacy of Vaccinium arctostaphylos in the treatment of hypertensive hyperlipidemic type 2 diabetic patients
- Conditions
- Diabetes mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT201701282288N11
- Lead Sponsor
- Vice Chancellor for Research, ACECR Institute of Medicinal Plants
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
Iranian male and female hypertensive hyperlipidemic type 2 diabetic outpatients; patients aged 40 to 60 years; patients with blood HbA1c levels between 7% and 9%; patients with fasting blood LDL levels between 100 mg/dL and 150 mg/dL; patients with systolic blood pressures between 14 and 16 mmHg; patients with diastolic blood pressures between 9 and 10 mmHg; patients taking 15 mg glibenclamide, 2 g metformin and 20 mg atorvastatin per day; patients taking synthetic antihypertensive drugs with 3 different mechanisms per day. Exclusion criteria: Patients taking other drugs effective on the blood glucose and lipid levels; patients with cardiac, renal, hepatic, hematological diseases, hypothyroidism, tachycardia, vertigo and seizure; patients with a history of gallstones or gall bladder surgery; pregnant women; women planning pregnancy; breast-feeding women.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of systolic blood pressure. Timepoint: 2 months. Method of measurement: 24-hour ambulatory blood pressure monitoring.;Amount of diastolic blood pressure. Timepoint: 2 months. Method of measurement: 24-hour ambulatory blood pressure monitoring.;Blood level of glycosylated hemoglobin. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of LDL-C. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).
- Secondary Outcome Measures
Name Time Method Blood level of HDL-C. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of total choletsterol. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of SGOT. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of SGPT. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of creatinine. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Fasting blood glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;2 hour postprandial blood glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Blood level of triglycerides. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).