CTRI/2026/03/0105781招募中4 期
Comparing regenerative potential of 1% Melatonin and Leukocyte-platelet rich fibrin (L-PRF) when used in treatment of periodontal defects – a Split mouth Clinico-Radiographic study
Self sponsor1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2026年3月20日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- melatonin group show good bone fill
研究概览
简要总结
There are studies evaluating efficiency of L-PRF in periodontal regeneration in intrabony defects .
There are no particular studies till date which compared the regenerative potential of Melatonin V/S LPRF in intrabony defects caused due to periodontitis.
This study is done to observe the amount of bone fill obtained when 1% melatonin is used to treat intrabony periodontal defects.
The aim of the present study is to compare and evaluate the regeneration of bone by using 1% Melatonin against L-PRF in periodontal intrabony defects using clinical and radiographic parameters
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •patient with no systemic disease ,probing pocket depth of 5 to 9 mm and horizontal defect depth of 3 to 5 mm.
排除标准
- •Patients with poor compliance.
- •Patients with smoking habit.
- •Pregnancy and lactation.
- •Patients with any systemic disease Patients with Blood disorders Patients under any medication which alter the bone metabolism Patients with malocclusion and parafunctional habits.
- •CBCT evaluation showing defect not suitable for grafting procedures.
结局指标
主要结局
melatonin group show good bone fill
时间窗: melatonin group show good bone fill at 6 months
次要结局
未报告次要终点
研究者
Dr kanike shravanth
Government dental collage and hospital Hyderabad
研究点 (1)
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