Comparative Evaluation of the Effectiveness of Autologous Sticky Bone with that of Autologous PRF and Octacalcium Phosphate-Coated Deproteinized Bovine Bone Graft Material in the Regeneratin of Human Periodontal Infrabony Defects- A Randomised Control Trial.
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Radiographic Bone Fill in Infrabony defects at 6 months post surgery.
研究概览
简要总结
Periodontal regeneration is challenging because it requires the predictable regeneration of three very distinct and varied tissues (such as cementum, PDL, and bone) as well as a triphasic contact between them in order to guarantee the repair. The aim of the current study will be to compare and evaluate the effectiveness of autologous sticky bone with that of autologous PRF and deproteinized, octacalcium phosphate-coated bovine bone graft material in the regeneration of human periodontal infrabony defects using clinical and radiographic data. Twenty individuals in good systemic health will be treated with autologous sticky bone (Group-A) and autologous PRF in combination with deproteinized, octacalcium phosphate-coated bovine bone graft material (Group-B) for twenty periodontal infrabony defects. Clinical and radiographic features will be evaluated before surgery and six months following the procedure. The final data will be subjected to statistical analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Presence of at least 1 or 2 radiographically detectable interproximal infrabony osseous defect with probing pocket depth ≥ 5 mm and clinical attachment loss ≥ 5 mm following initial therapy.
- •Depth of intraosseous component of the defect ≥ 3 mm by clinical and radiographic means, which will be confirmed on intra-surgical measurement.
- •A radiographic base of the defect at least 3 mm coronal to the apex of the tooth.
- •Presence of at least 3 mm width of keratinized gingiva around test teeth to allow complete soft tissue coverage of the defect.
排除标准
- 未提供
结局指标
主要结局
Radiographic Bone Fill in Infrabony defects at 6 months post surgery.
时间窗: 6 months
次要结局
- 1)Gain in Clinical Attachment Level(CAL)(2)Reduction in Probing Pocket Depth)
研究者
Dr Sakshi Kotecha
Sharad Pawar Dental College