Improving Treatment of Major Depressive Disorder by Reducing Negative Future-Oriented Mental Imagery

Not Applicable

Recruiting

• Conditions: Major Depressive Disorder; Mental Imagery; Cognitive Behavioral Therapy

• Registration Number: NCT06454695
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-5-23
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Inclusion Criteria:<br><br> - Aged 18 years or older;<br><br> - Meet DSM-5 criteria for major depressive disorder;<br><br> - Presence of 1-3 negative future-oriented mental images, which cause distress;<br><br> - Be able to understand questionnaires and study information letter;<br><br> - In case of medication use: are stable on medication for six weeks or longer.<br><br>Exclusion Criteria:<br><br> - Current or history of psychotic disorder;<br><br> - Current or history of bipolar disorder;<br><br> - Severe cognitive impairment (e.g., mental retardation) as evidenced by educational<br> records, parental report and/or clinical impression;<br><br> - Current EMDR or imagery rescripting therapy;<br><br> - Other circumstances that might affect participation (e.g., severe medical disorder,<br> relocation).

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Beck Depression Inventory (Acceptability);Behavioral Activation for Depression Scale (Acceptability);Session Rating Scale (Treatment satisfaction);Client satisfaction Questionnaire (treatment satisfaction)

Secondary Outcome Measures

Name	Time	Method
Recruitment/admission ratio (Feasibility);Dropout (Feasibility);(serious) adverse events (Feasibility);Variance of effect