Volatile organic compounds in exhaled breath for the detection of interstitial lung disease (VISION)
Completed
- Conditions
- lung fibrosis10006436
- Registration Number
- NL-OMON52688
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 180
Inclusion Criteria
Eligible for participation in this study are all patients (>= 18 years of age):
- with a known diagnosis of ILD (based on high resolution chest CT obtained in
usual care)
- at risk for ILD (based on suspected diagnosis, chest X-ray, complaints or
abnormal lung function obtained in usual care)
- without ILD (other diagnosis)
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- Recent (< 12 hours) intake of alcohol (checked by anamnesis of the study
subject)
- Unwillingness or inability to comply with the study protocol for any other
reason
In order to increase the applicability in clinical practice, there are no
further restrictions.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To determine the diagnostic accuracy of exhaled breath analysis by eNose at<br /><br>point of care for discrimination between patients with ILD,at risk for ILD<br /><br>(including post COVID-19 patients) and without ILD. </p><br>
- Secondary Outcome Measures
Name Time Method <p>To assess the accuracy of exhaled breath analysis by eNose at baseline and<br /><br>follow-up to identify diagnostic markers for early diagnosis and disease<br /><br>progression of ILD. </p><br>