NL-OMON31214已完成不适用
Volatile organic compounds in breath as marker of asthma and COPD: studies on methodologic aspects - VOC in breath: methodological aspects
Medisch Centrum Leeuwarden0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Study 1;COPD patients:
- •Adults between 40-65 years
- •Lungfunction: FEV1/VC< 70% and FEV1 30-80%pred. (GOLD II-IV ) (21)
- •Actual smoker(>10 cigarettes/day, >10 packyears)
- •Adults between 40-65 years
- •Healthy with a negative history on lung diseases or any other illness.
- •Prebronchodilator FEV1 > 80% predicted, FEV1/FVC > 0.70 (22)
- •Actual smoker(>10 cigarettes/day, > 10 packyears);Study 2;COPD patients:
- •Adults between 40-65 years
- •Lungfunction: FEV1/VC< 70% and FEV1 30-80%pred (GOLD II-IV ) (21)
- •Non-smoker(> 1 year, > 10 packyears)
- •Adults between 40-65 years
- •Healthy with a negative history on lung diseases or any other illness.
- •Prebronchodilator FEV1 > 80% predicted, FEV1/FVC > 0.70 (22)
- •Actual non-smoker(> 1 year);Study 3;COPD patients:
- •Adults between 40-65 years
- •Lungfunction: FEV1/VC< 70% and FEV1 30-80%pred (GOLD II-IV ) (21)
- •Non-smoker(>1 year, > 10 packyears)
- •Asthma patients:
- •Adults between 40-65 years
- •episodic chest symptoms, documented reversibility in FEV1 by 400 µg inhaled salbutamol > 12 %pred or airway hyperresponsiveness (PC20 methacholine < 8 mg/ml) [15], with or without atopy
- •Non-smoker(>1 year,< 10 packyears)
排除标准
- •Other pulmonary diseases
- •Diabetes mellitus (documented in the past)
- •Hypercholesterolaemia (documented in the past)
- •Exacerbation < 6 weeks
- •Any infection (especially of the airways) in the last 4 weeks
- •Inhalation medication < 4 hours
- •parodontitis
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