Resistance Training in Diabetic Elder Patients

Not Applicable

Completed

• Conditions: Diabetes Mellitus, Type 2
• Interventions: Behavioral: Usual care; Behavioral: Resistance exercise

• Registration Number: NCT01638351
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The purpose of this study is to investigate the effect of a 12-week progressive resistance training program on the skeletal muscle function, glycemic control, functional capacity, and quality of life in the elderly with type 2 diabetes mellitus.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-12
• Study First Submitted: 2012-07-08
• Study First Submitted QC: 2012-07-08
• Study First Posted: 2012-07-11
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Status Verified: 2012-11
• Last Update Submitted: 2012-11-15
• Last Update Posted: 2012-11-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• 65 years old or older
• no clinical diagnosis of cardiovascular disease
• patients with or without type 2 diabetes mellitus

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Exclusion Criteria

• glycated hemoglobin > 10%
• pulmonary disease
• cancer
• cognitive dysfunction
• any neurological or musculoskeletal disease that will affect exercise performance

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Usual care	Usual care	Participants in this arm will receive a brochure specific for type 2 diabetes mellitus about the general principles of exercise, nutrition, and diet. They are asked to maintain their activity level.
Resistance exercise	Resistance exercise	Progressive resistance training, 3 times a week for 12 weeks

Primary Outcome Measures

Name	Time	Method
Maximal muscle strength	Twelve weeks	This outcome measure includes upper and lower body maximal muscle strength.

Secondary Outcome Measures

Name	Time	Method
Physical body function	Twelve weeks	This outcome will be assessed by one minute sit-to-stand test and timed "Up and Go" test.
Quality of life	Twelve weeks	This outcome measure will be assessed by the diabetes-specific questionnaire.
Waist circumference	Twelve weeks
Body mass index	Twelve weeks	This outcome measure includes the measurements of body height and body weight.
Functional capacity	Twelve weeks	Peak oxygen consumption will be determined by graded exercise test to assess functional capacity.
Blood biochemical parameters	Twevle weeks	This outcome measure includes the analysis of fasting glucose, glycated hemoglobin, lipid profile, C-reactive protein, and related metabolites.
Muscle oxygenation	Twelve weeks	Muscle oxygenation will be assessed during exercise

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei City, Taiwan