Study for the screening of TCM syndrome classification and molecular diagnostic markers in patients with cognitive impairment after strok

Phase 1

Recruiting

• Conditions: post-stroke cognitive impairment

• Registration Number: ITMCTR1900002390
• Lead Sponsor: Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients without cognitive impairment who met the diagnostic criteria and classification criteria of this study; Patients with mild and moderate PSCI after stroke were divided into phlegm-dampness syndrome group and non-phlegm-dampness syndrome group;
2. The history of stroke is confirmed by CT or MRI, and cognitive dysfunction must occur after cerebrovascular disease;
3. Life sign is stable, consciousness is sober;
4. Aged 35 to 70 years old;
5. Volunteer to participate in this research project.

Exclusion Criteria

1. Complicated with severe primary diseases of the heart, liver, kidney and hematopoietic system;
2. Acute disturbance of consciousness;
3. Mild cognitive impairment was present before the stroke;
4. Other causes of dementia and brain dysfunction are mental and physical disorders;
5. With serious impairment of vision or hearing or speech interferes with rehabilitation;
6. In addition to cognitive impairment, there were no other focal signs and symptoms of cerebrovascular disease.

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The differential proteins in plasma of each group were observed to search for key molecular markers;