The Ratio of Femoral Vein Diameter to Femoral Artery Diameter to Predict Fluid Responsiveness in Children

Completed

• Conditions: Pediatric ALL; Fluid Overload

• Registration Number: NCT05992246
• Lead Sponsor: Tanta University

Brief Summary

The hypothesis of the study will be that the ratio of femoral vein diameter to femoral artery diameter will have correlation with fluid status in pediatrics.

Detailed Description

Proper administration of intravenous fluids is an important part of treating circulatory failure in children and affects the clinical outcome of the management of the child's emergency. Giving a small amount of fluid will cause tissue hypoperfusion and worsen organ dysfunction and cause ischemia. On the other hand, excess fluid interferes with oxygen delivary, exacerbates treatment outcomes, increases complications, and extends both the length of the stay in intensive care and mortality. The use of bedside ultrasound by pediatric intensive care physicians has become so critical in recent years that it is now a component of physical examination in ICUs

Study Timeline

• Study First Submitted: 2023-08-08
• Study First Submitted QC: 2023-08-08
• Study First Posted: 2023-08-15
• Study Start: 2023-08-20
• Primary Completion: 2024-12-30
• Study Completion: 2025-01-30
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-03
• Last Update Posted: 2025-02-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• children with American society of anaesthesiologist physical status 1-2
• 2-10 years of age
• scheduled for elective surgery
• signs of moderate to severe dehydration

Exclusion Criteria

• Patients with mild dehydration.
• Patients with history of significant comorbid conditions or previous laparotomy.
• Congenital heart disease.
• Heart failure.
• Disorder of venous return like arteriovenous fistula, DVT or Varicose veins.
• Increase intra-abdominal pressure.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of changes in the ratio of femoral vein diameter to femoral artery diameter	immediate preoperative period before the induction of general anesthesia	Measurement of changes in the ratio of femoral vein diameter to femoral artery diameter before and after fluid challenge which will be defined as infusion of ringer lactate 10 ml/kg body weight over 20 min.

Trial Locations

Locations (1)

Faculty of medicine, Tanta university; 🇪🇬 Tanta, El Gharbyia, Egypt