Dexamethasone and Lidocaine Wound Infiltration for Post-cesarean Analgesia

Phase 2

Completed

• Conditions: Post-Cesarean delivery Pfannenstiel incision pain; Caesarean delivery; Pain; Dexamethasone; Lidocaine

• Registration Number: TCTR20220524002
• Lead Sponsor: Thammasat University Research Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-24
• Study Completion: 2022-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 279

Inclusion Criteria

Pregnant women who have indication for Cesarean delivery

Exclusion Criteria

1. Allergic history to dexamethasone, lidocaine, or adrenaline
2. Overt diabetes mellitus, or gestational diabetes mellitus who required insulin therapy
3. Cardiovascular disease, pheochromocytoma, or active hyperthyroidism
4. Active phase of labor
5. COVID-19 infection
6. General anesthesia on Cesarean delivery
7. Cesarean hysterectomy
8. Delayed primary suture

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score At 2, 4, 6, 12, 18, and 24 hours post-operation Visual Analogue Scale

Secondary Outcome Measures

Name	Time	Method
Post-operative nausea and vomiting Within 24 hours post-operation Injection of specific symptomatic drugs,Post-operative itching Within 24 hours post-operation Injection of specific symptomatic drugs,Post-operative abdominal bloating Within admission Given of specific symptomatic drugs,Post-operative pain reliver Within 24 hours post-operation Injection of meperidine,Post-operative alternative pain reliver Within 24 hours post-operation Injection of alternative pain reliver drugs, besides meperidine