CTRI/2014/12/005307
Completed
未知
COGNITIVE, NEUROPHYSIOLOGICAL & NEUROIMAGING CORRELATES OF THE EFFECT OF TRANSCRANIAL DIRECT CURRENT STIMULATION ON AUDITORY VERBAL HALLUCINATIONS IN SCHIZOPHRENIA
ational Institute of Mental Health and Neurosciences0 sites25 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- ational Institute of Mental Health and Neurosciences
- Enrollment
- 25
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Diagnosis of schizophrenia / schizophreniform disorder as per DSM\-V criteria (Diagnostic and Statistical Manual for Mental Disorders, American Psychiatric Association, 2013\);
- •2\) Clinically Significant Auditory Verbal Hallucinations as defined by the Auditory Hallucination Rating Scale (Haddock et al., 1999\) items on frequency, duration and disruption each having a score \= 2;
- •3\) Persistence of Auditory Verbal Hallucinations as denoted by daily hallucinations without remission despite adequate treatment with antipsychotic medication at an adequate dosage for at least 3 months (Brunelin et al., 2012a)
- •4\) Age range: 18 – 45 years;
- •5\) Both sexes;
- •6\) Right Handedness and
- •7\) Written informed consent.
Exclusion Criteria
- •1\. Features suggestive of psychiatric emergency (for example: suicidal risk, aggression, excitement, catatonia, prolonged nutritional deprivation or any other status requiring intensive clinical care)
- •2\. Pregnancy or post\-partum status
- •3\. Any contraindication to tDCS procedure (metal in the head, implanted brain medical devices, local lesion or injury in the scalp / head)
- •4\. Any contraindication for MRI
- •5\. Any co\-morbid psychiatric or neurological diagnosis
- •6\. Left/Mixed Handedness
Outcomes
Primary Outcomes
Not specified
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