COGNITIVE, NEUROPHYSIOLOGICAL & NEUROIMAGING CORRELATES OF THE EFFECT OF TRANSCRANIAL DIRECT CURRENT STIMULATION ON AUDITORY VERBAL HALLUCINATIONS IN SCHIZOPHRENIA

ational Institute of Mental Health and Neurosciences0 个研究点目标入组 25 人开始时间: 待定最近更新: 2024年1月22日

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•1) Diagnosis of schizophrenia / schizophreniform disorder as per DSM-V criteria (Diagnostic and Statistical Manual for Mental Disorders, American Psychiatric Association, 2013);
•2) Clinically Significant Auditory Verbal Hallucinations as defined by the Auditory Hallucination Rating Scale (Haddock et al., 1999) items on frequency, duration and disruption each having a score = 2;
•3) Persistence of Auditory Verbal Hallucinations as denoted by daily hallucinations without remission despite adequate treatment with antipsychotic medication at an adequate dosage for at least 3 months (Brunelin et al., 2012a)
•4) Age range: 18 – 45 years;
•5) Both sexes;
•6) Right Handedness and
•7) Written informed consent.

•1. Features suggestive of psychiatric emergency (for example: suicidal risk, aggression, excitement, catatonia, prolonged nutritional deprivation or any other status requiring intensive clinical care)
•2. Pregnancy or post-partum status
•3. Any contraindication to tDCS procedure (metal in the head, implanted brain medical devices, local lesion or injury in the scalp / head)
•4. Any contraindication for MRI
•5. Any co-morbid psychiatric or neurological diagnosis
•6. Left/Mixed Handedness

发起方

ational Institute of Mental Health and Neurosciences