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A physical activity intervention to delay the progression of cerebrovascular disease in older adults with mild memory problems

Not Applicable
Completed
Conditions
Mild cognitive impairment (MCI)
Subjective Memory Complaints (SMC)
Cerebrovascular disease
Neurological - Dementias
Registration Number
ACTRN12611000612910
Lead Sponsor
The University of Melbourne
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
156
Inclusion Criteria

Community dwelling
Diagnosis of SMC or MCI
Presence of at least one CVD risk factor
English Speaker
Willingness and ability to provide written informed consent

Exclusion Criteria

Baseline Mini-Mental State Examination (MMSE) score < 24
Diagnosis of dementia
Unable to undergo MRI or PET scans
Geriatric Depression Scale (GDS-15) score > 6
Unstable or life threatening disease or illness that could lead to difficulty complying with the protocol
Medical condition that contraindicates physical activity
Severe visual or auditory impairment
History of chronic alcohol abuse within the past 5 years
Unable to attend the follow-up assessments

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Progression of cerebrovascular disease (CVD) as measured by MRI[24 months following randomisation]
Secondary Outcome Measures
NameTimeMethod
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